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Tactile corpuscle

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Tactile corpuscle
Papilla of the hand, magnified 350 times.
  1. Side view of a papilla of the hand.
    1. Cortical layer.
    2. Tactile corpuscle.
    3. Small nerve of the papilla, with neurolemma.
    4. Its two nerve fibers (axons) running with spiral coils around the tactile corpuscle.
    5. Apparent termination of one of these fibers.
  2. A tactile papilla seen from above so as to show its transverse section.
    1. Cortical layer.
    2. Nerve fiber.
    3. Outer layer of the tactile body, with nuclei.
    4. Clear interior substance.
Latincorpusculum tactus
Anatomical terms of microanatomy

Tactile corpuscles or Meissner's corpuscles are a type of mechanoreceptor discovered by anatomist Georg Meissner (1829–1905) and Rudolf Wagner.[1][2] This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to pressure. In particular, they have their highest sensitivity (lowest threshold) when sensing vibrations between 10 and 50 hertz. They are rapidly adaptive receptors. They are most concentrated in thick hairless skin, especially at the finger pads.


Tactile corpuscles are encapsulated myelinated nerve endings,[3] surrounded by Schwann cells.[3] The encapsulation consists of flattened supportive cells arranged as horizontal lamellae surrounded by a connective tissue capsule. The corpuscle is 30–140 μm in length and 40–60 μm in diameter. A single nerve fiber meanders between the lamellae and throughout the corpuscle.[citation needed]


They are distributed on various areas of the skin, but concentrated in areas especially sensitive to light touch, such as the fingers, lips and male prepuce.[4][5][6][7][8][9] More specifically, they are primarily located in glabrous skin just beneath the epidermis within the dermal papillae.[10]

Comparison with other receptors[edit]

Feelings of deep pressure (from a poke, for instance) are generated from lamellar corpuscles (the only other type of phasic tactile mechanoreceptor), which are located deeper in the dermis, and some free nerve endings.

Also, tactile corpuscles do not detect noxious stimuli; this is signaled exclusively by free nerve endings.


The number of tactile corpuscles per square millimeter of human skin on the fingertips drops fourfold[clarification needed] between the ages of 12 and 50. The rate at which they are lost correlates well with the age-related loss in touch sensitivity for small probes.[11][clarification needed]


Tactile corpuscles are rapidly adapting mechanoreceptors. They are sensitive to shape and textural changes in exploratory and discriminatory touch. Their acute sensitivity provides the neural basis for reading Braille text. Because of their superficial location in the dermis, these corpuscles are particularly sensitive to touch and vibrations, but for the same reasons, they are limited in their detection because they can only signal that something is touching the skin.[12]

Any physical deformation of the corpuscle will cause sodium ions to enter it, creating an action potential in the corpuscle's nerve fiber. Since they are rapidly adapting or phasic, the action potentials generated quickly decrease and eventually cease (this is the reason one stops "feeling" one's clothes).[12]

If the stimulus is removed, the corpuscle regains its shape and while doing so (i.e.: while physically reforming) causes another volley of action potentials to be generated.[citation needed]

Additional images[edit]


  1. ^ "Georg Meissner". www.WhoNamedIt.com. Retrieved 30 January 2017.
  2. ^ Paré, Michel; Joseph E. Mazurkiewicz; Allan M. Smith; Frank L. Rice (15 September 2001). "The Meissner Corpuscle Revised: A Multiafferented Mechanoreceptor with Nociceptor Immunochemical Properties". The Journal of Neuroscience. 21 (18): 7236–46. doi:10.1523/JNEUROSCI.21-18-07236.2001. PMC 6763005. PMID 11549734.
  3. ^ a b "Meissner's Corpuscles | AnatomyBox". Retrieved 2020-10-22.
  4. ^ Cauna, Nikolajs; Ross, Leonard L. (1 October 1960). "The fine structure of Meissner's touch corpuscles of human fingers". The Journal of Cell Biology. 8 (2): 467–82. doi:10.1083/jcb.8.2.467. PMC 2224947. PMID 13691669.
  5. ^ Hoffmann, Joscelyn N.; Montag, Anthony G.; Dominy, Nathaniel J. (November 2004). "Meissner corpuscles and somatosensory acuity: the prehensile appendages of primates and elephants". The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology. 281 (1): 1138–47. doi:10.1002/ar.a.20119. PMID 15470674.
  6. ^ Martini / Bartholomew (2010) [1995]. Essentials of Anatomy and Physiology 3E. Pearson Benjamin Cummings.
  7. ^ Afifi, Adel K.; Ronald Arly Bergman (2005) [1998]. Functional neuroanatomy: text and atlas. McGraw-Hill Professional. p. 16. ISBN 978-0-07-001589-0. 10.1036/0071408126.
  8. ^ "Nervous system - Touch". BBC. Retrieved 7 May 2010.
  9. ^ García-Mesa, Yolanda; García-Piqueras, Jorge; Cobo, Ramón; Martín-Cruces, José; Suazo, Iván; García-Suárez, Olivia; Feito, Jorge; Vega, José A. (12 June 2021). "Sensory innervation of the human male prepuce: Meissner's corpuscles predominate". Journal of Anatomy. 239 (4): 892–902. doi:10.1111/joa.13481. PMC 8450466. PMID 34120333.
  10. ^ Winkelmann, R. K. (1959-01-21). "The Erogenous Zones: Their Nerve Supply and Significance". Proceedings of the Staff Meetings of the Mayo Clinic. 34 (2): 39–47. PMID 13645790.
  11. ^ Thornbury, Julia M.; Mistretta, Charlotte M. (January 1981). "Tactile sensitivity as a function of age". Journal of Gerontology. 36 (1): 34–9. doi:10.1093/geronj/36.1.34. PMID 7451834.
  12. ^ a b Bear, Mark F.; Connors, Barry W.; Paradiso, Michael A. (2016). Neuroscience : Exploring the Brain (4th ed.). Philadelphia: Wolters Kluwer. pp. 416–422. ISBN 9780781778176. OCLC 897825779.


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